Methods and compound mixtures for determining protein activity using nmr spectroscopy
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United States of America Patent
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Issued Date -
Oct 20, 2005
app pub date -
May 9, 2005
filing date -
Apr 19, 2002
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Abandoned
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Abstract
The invention relates to methods for determining protein activity using NMR spectroscopy. The present invention provides a method for determining protein activity in vivo using probe compounds and enhancing the nuclear polarisation of NMR active nuclei present in the probe compounds (hereinafter termed 'hyperpolarisation') prior to NMR analysis. The invention also provides mixtures of probe compounds for the above-mentioned method.
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