Plant germplasm

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United States of America Patent

SERIAL NO

11038228

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Abstract

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A recombinant plant genome contains a gene cascade such that it is incapable of producing a mature plant but requires the presence of a chemical inducer. The gene cascade includes a gene switch which is inducible by external application of a chemical inducer and which controls expression of a gene product which affects expression of a second gene in the genome. Survival or development of the plant is dependant upon either expression or non-expression of the second gene and application of the inducer, therefore, selects whether or not the plant develops. In one example the second gene encodes a cytotoxic molecule and expression of that gene is fatal to the plant. In another example the second gene encodes a desirable characteristic which may be excised selectively by applying or withholding chemical application. The second gene may be placed under control of a development regulated promoter.

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Patent Owner(s)

Patent OwnerAddress
ZENECA LIMITED15 STANHOPE GATE LONDON W1Y 6LN UNITED KINGDOM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greenland, Andrew James Maidenhead, GB 16 154
Jepson, Ian Slough, GB 20 184
Jonathan, Bright Simon William Marlow, GB 1 2
Paine, Jacqueline Ann Mary Bracknell, GB 4 2

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