Methylenetetrahydrofolate reductase inhibitors and use thereof
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United States of America Patent
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Issued Date -
Oct 6, 2005
app pub date -
Apr 23, 2004
filing date -
Dec 3, 2001
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Abandoned
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Abstract
The present invention provides methylenetetrahydrofolate reductase (MTHFR) inhibitors, such as antisense oligonucleotides, for use in selective inhibition of cancer cell growth in a mammal. The present invention further provides methods of using the MTHFR inhibitors, alone or in combination with one or more standard chemotherapeutics, for selective inhibition of cancer cell growth.
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