Methods and products based on oligomerization of stress proteins
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United States of America Patent
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Issued Date -
Oct 6, 2005
app pub date -
Mar 14, 2005
filing date -
Feb 28, 2002
priority date (Note) -
Abandoned
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Abstract
In one aspect, the invention provides methods for determining the biological activity of heat shock proteins or heat shock protein-peptide complexes based on the ATPase activity or the multimeric structure of the heat shock proteins or heal shock protein-peptide complexes, and methods for screening agents that modulate the biological activity of heat shock proteins or heat shock protein-peptide complexes. In another aspect, the invention provides complexes, compositions and methods for enhancing the immunogenicity of a heat shock protein or a complex comprising a heal shock protein and an antigenic molecule.
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