Surgical adhesive formulations and methods of preparation
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United States of America Patent
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Issued Date -
Sep 29, 2005
app pub date -
Mar 29, 2005
filing date -
Mar 29, 2004
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Abandoned
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Abstract
This application describes specific ratios of raw ingredients and methods of combining and reacting those ingredients to obtain polyurethane prepolymers optimized for the special purpose of forming bonds to living tissue, or of bulking or sealing it. Preferred prepolymers are based on polyalkylene oxides, particular copolymers of ethylene oxide and propylene oxide. Important method steps are rigorous drying and deionization, and rigorous control of temperature during synthesis and use.
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