Phenylalanine derivatives

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United States of America Patent

APP PUB NO 20050215598A1
SERIAL NO

11130531

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Abstract

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Phenylalanine derivatives of formula (1) are described: 1 wherein R is a carboxylic acid or a derivative thereof; L.sup.1 is a linker atom or group; Ar is an optionally substituted aromatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of alpha4 integrins to their ligands and are of use in the prophylaxis and treatment of immune or inflammatory disorders.

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Patent Owner(s)

Patent OwnerAddress
CELLTECH R&D LTD208 BATH ROAD SLOUGH BERKSHIRE SL1 3WE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Archibald, Sarah Catherine Maidenhead, GB 32 292
Head, John Clifford Maidenhead, GB 35 418
Porter, John Robert Chinnor, GB 68 431
Warrellow, Graham John Northwood, GB 62 965

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