Method for determining reduced susceptibility of HIV to protease inhibitor treatment
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United States of America Patent
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Issued Date -
Sep 29, 2005
app pub date -
Feb 4, 2005
filing date -
Feb 6, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides methods and devices for predicting whether a HIV variant will be resistant to an antiviral drug based on the variant's genotype. In one aspect, methods are provided comprising determining whether a combination of protease inhibitor resistance mutations meet certain conditions, as disclosed herein, thereby assessing the effectiveness of ritonavir-boosted indinavir therapy in the HIV-infected subject. Computer implemented methods comprising determining HIV resistance are provided.
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