Substrate and method for measuring the electrophysiological properties of cell membranes
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United States of America Patent
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Issued Date -
Sep 29, 2005
app pub date -
May 23, 2005
filing date -
Apr 17, 2002
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a substantially planar substrate for use in patch clamp analysis of the electrophysiological properties of a cell membrane comprising a glycocalyx, wherein the substrate comprises an aperture having a rim, the rim being adapted to form a gigaseal upon contact with the cell membrane. The invention further provides a method of making such a substrate and method for analysing the electrophysiological properties of a cell membrane comprising a glycocalyx.
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