High-density ion transport measurement biochip devices and methods
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United States of America Patent
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Issued Date -
Sep 8, 2005
app pub date -
Jan 10, 2005
filing date -
Mar 24, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention provides novel biochips, biochip-based devices, and device configurations that can be used for ion transport measurement. The chips, devices, and designs of the present invention are particularly suited to high-throughput assays such as compound screening assays using patch clamping techniques. The invention includes high-density biochips made by novel methods and methods of making high density biochips, and also provides novel upper chamber configurations and fluidics designs for upper chambers of ion transport measurement devices that can be used in high throughput patch clamp assays. The present invention also includes methods of using ion transport measuring chips and devices of the present invention.
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