Method for reducing measuring bias in amperometric biosensors
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United States of America Patent
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Issued Date -
Sep 8, 2005
app pub date -
Mar 1, 2005
filing date -
Mar 3, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides a method for determining the concentration of an analyte in a test sample, comprising the following steps: (a) assembling an amperometric biosensor, which comprises at least an electrode system and an electric mediator for redox, and applying a predetermined potential to the electrode system; (b) applying a test sample to the biosensor and immediately gradually lowering the predetermined potential to a value unable to drive the electrochemical redox of the electric mediator; (c) after a sufficient reaction time, applying a second potential to the electrode system of the biosensor to drive the electrochemical redox of the electric mediator; and (d) measuring the electrochemical current of the electrode system and determining the concentration of the analyte.
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