Mass spectrometric concentration measurement of proteins

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United States of America Patent

APP PUB NO 20050191677A1
SERIAL NO

11054621

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the determination of the relative concentrations of proteins or protein derivatives in liquids. The invention provides a method which uses nanoparticles coated with specific affinity collectors in order to fish the desired proteins or protein derivatives out of the liquids and to separate them, in order to introduce them to the mass spectrometric frequency analysis after elution from the affinity collectors. This makes it possible to determine the concentrations of several proteins or several forms of protein modification or mutation relative to each other with relatively high measuring dynamics.

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Patent Owner(s)

Patent OwnerAddress
BRUKER DALTONIK GMBH28359 BREMEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Franzen, Jochen Bremen, DE 156 4040
Suckau, Detlev Grasberg, DE 13 104

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