Methods of treating sepsis

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United States of America Patent

APP PUB NO 20050187257A1
SERIAL NO

11092939

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention features a method for treating sepsis. The method includes administrating to a subject in need thereof an effective amount of a fused pyrazolyl compound of formula (I): 1 A is H, C.sub.1.about.C.sub.6 alkyl, or 2 in which n is 0, 1, 2, or 3; each of Ar.sub.1, Ar.sub.2, and Ar.sub.3, independently, is phenyl, pyridinyl, thienyl, furyl, or pyrrolyl; and each of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6, independently, is XYZ; or R.sub.1 and R.sub.2 together, R.sub.3 and R.sub.4 together, or R.sub.5 and R.sub.6 together are O(CH.sub.2).sub.1-6O; in which X is a bond or C.sub.1.about.C.sub.6 alkylene, Y is a bond, O, S, OC(O), OC(O)(CH.sub.2).sub.1-6C(O)O, C(O)O, C(O)S, C(O)NH, C(O)NC.sub.1.about.C.sub.6 alkyl, NH, or NC.sub.1.about.C.sub.6 alkyl, and Z is H, halogen, CN, NO.sub.2, or C.sub.1.about.C.sub.6 alkyl; and provided that one of R.sub.3 and R.sub.4 is not H.

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Patent Owner(s)

Patent OwnerAddress
YUNG SHIN PHARMACEUTICAL IND CO LTD A TAIWAN CORPORATIONNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guh, Jih-Hwa Taipei, TW 16 246
Kuo, Sheng-Chu Taichung, TW 57 348
Lee, Fang-Yu Tachia Taichung, TW 33 261
Pan, Shiow-Lin Taipei, TW 29 173
Teng, Che-Ming Taipei, TW 52 378

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