Room temperature storage of organs
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United States of America Patent
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app pub date -
May 28, 2004
filing date -
May 30, 2003
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Abandoned
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Abstract
The present invention relates generally to compositions and method for freezing and/or drying organs for storage prior to use. In particular, the present invention relates to the genetic modification of cells used to form organs so that organs formed from the genetically modified cells can be dried. According to the invention, mammalian cells may be modified with genes encoding plant late embryogenesis protein HVA1, trehalose transport protein, or a trehalose synthesis pathway. The invention also provides methods of treating patients with organs that have been preserved by freezing and/or drying.
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