Nucleic acid isolated from the 5' nontranslated region (5'NTR) end of the human FGF-1 gene having IRES activity
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app pub date -
Dec 22, 2004
filing date -
Jun 27, 2002
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Abandoned
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Abstract
The invention relates to an isolated nucleic acid of the human FGF-1 gene having IRES (internal ribosome entry site) activity, said nucleotide sequence being derived from the 5' non-translated region (5'NTR) end of the human FGF-1 gene. The invention also concerns an expression cassette of at least one molecule of interest in a eukaryotic cell comprising at least one of said sequences. The cassette can be inserted directly or in the form of a vector in a host cell, hence the invention further relates to the recombinant vectors and the host cell transfected by said vector or the cassette.
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