Indole derivatives

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United States of America Patent

APP PUB NO 20050171185A1
SERIAL NO

11092398

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A novel indole derivative or a salt thereof is provided, which is represented by the formula: 1 wherein R.sub.1 represents an aryl lower alkyl group, said aryl group may be substituted with one or more groups selected from the group consisting of a halogen atom, an aryl group, a heterocyclic group, an aryl lower alkyl group, an aryl lower alkenyl group, a halo-lower alkyl group, a lower cycloalkyl-lower alkoxy group, a lower cycloalkoxy-lower alkyl group, an aryl lower alkynyl group, an aryloxy lower alkyl group, an aryl lower alkoxy group, a lower alkylthio group, a lower alkoxy group, and an alkenyl group; and R.sub.2 represents a lower alkyl group, a lower alkenyl group, an aryl group, or a heterocyclic group, each of which may be substituted with a hydrogen atom, a lower alkyl group, a lower alkenyl group, or an aryl group. The compound of the present invention has blood sugar level-depressing activity and PDE5-inhibiting activity, and is useful as medicine.

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Patent Owner(s)

Patent OwnerAddress
FUJISAWA PHARMACEUTICAL CO LTD A JAPANESE CORPORATIONNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hiramura, Takahiro Arai-shi, JP 30 302
Imoto, Takafumi Arai-shi, JP 16 276
Kayakiri, Hiroshi Osaka, JP 47 671
Oku, Chikako Osaka, JP 3 17
Oku, Noriko Osaka, JP 4 20
Oku, Teruo Osaka, JP 85 1191
Oku, Tomohito Osaka, JP 3 17
Onomura, Osamu Nagasaki-shi, JP 11 150
Yamasaki, Noritsugu Himeji-shi, JP 30 303

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