Polysaccharide extract from Lycium barbarum as neuroprotective agent against beta-amyloid peptide neurotoxicity
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Issued Date -
Aug 4, 2005
app pub date -
Feb 3, 2005
filing date -
Feb 4, 2004
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Abstract
Extracts of Lycium barbarum serve as a neuroprotective agent against .beta.-amyloid peptide neurotoxicity which thus permits their use for the treatment of Alzheimer's disease (AD) and for the prevention of neuronal loss in aging against the accumulation of .beta.-amyloid peptide in the brain. Stress kinases (c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase) are used as a technological platform for screening neuroprotective drugs.
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