Compounds and methods for modulating adhesion molecule function
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United States of America Patent
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Issued Date -
Jul 28, 2005
app pub date -
Oct 1, 2004
filing date -
Jul 10, 1998
priority date (Note) -
Abandoned
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Abstract
Modulating agents and methods for enhancing or inhibiting cadherin-mediated functions are provided. The modulating agents comprise at least an HAV binding motif, an analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a motif. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material.
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