Temperature-stable formulations, and methods of development thereof
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United States of America Patent
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N/A
Issued Date -
Jul 14, 2005
app pub date -
Dec 16, 2004
filing date -
Dec 24, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
One embodiment of the present invention relates to a method of preparing a concentrated pharmaceutical formulation, comprising the steps of: combining in a container a therapeutic agent, a solvent and at least one pharmaceutically acceptable excipient to give a solution; adding to said solution a seed crystal of said compound to give a heterogeneous mixture; and observing the stability of said heterogeneous mixture.
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