Method for estimating or predicting the anti-tumor activity of a compound and for estimating or predicting the tumor growth in mammals
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
N/A
app pub date -
Sep 15, 2004
filing date -
Mar 15, 2002
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The present invention relates to a method for estimating or predicting anti-tumor activity of a compound and for estimating or predicting the tumor growth in mammals; the estimation comprises a) measuring the tumor weight in time; b) measuring the concentration of the compound in time; c) calculating kinetic parameters of the tumor growth: -a parameter (L.sub.0), representative of the portion of tumor cells present at the instant t.sub.0=0 that succeeds in taking root and in starting tumor cells proliferation in the mammals; -an index (.lambda..sub.0) of the production rate of tumor cells during an exponential phase of tumor growth; -an index (.lambda..sub.1) of tumor cells mass produced in the time unit during a linear phase of the tumor growth; and pharmacodynamic parameters: -an index (K.sub.1) of tumor cells death rate; -an index (K.sub.2) of the potency of the compound; and d) calculating tumor growth curves.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully