Matrix with noise reduction additive and disposable target containing the same
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United States of America Patent
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Issued Date -
Jun 23, 2005
app pub date -
Dec 21, 2004
filing date -
Dec 23, 2003
priority date (Note) -
Abandoned
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Abstract
A matrix for mass spectrometry, the matrix comprising an additive that minimizes or eliminates adduct formation and/or chemical noise generation is disclosed. Also disclosed is a method for depositing a matrix on a MALDI target plate and a disposable plate having a dissolvable pre-matrix deposited thereon. The matrix material can be 2,5-dimethoxybenzoic acid and a monobasic or dibasic salt or tribasic salt as an adduct-reducing additive, such as ammonium monobasic phosphate and sulfate salts, dibasic citrate salts and tribasic citrate salts.
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