Methods of diagnosing or treating Alzheimer's disease on basis of increased cerebrospinal fluid levels of nerve growth factor
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United States of America Patent
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app pub date -
Nov 15, 2004
filing date -
May 3, 1999
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Abstract
A method for diagnosing or prognosing Alzheimer's disease in a subject, or determining whether a subject is at increased risk of developing Alzheimer's disease, involves determining a level, or an activity, or both the level and the activity, of nerve growth factor in a sample taken from cerebrospinal fluid of the subject, and comparing the level, or the activity, or both the level and the activity, to a reference value representing a known disease or health status, wherein a varied level, or activity, or both the level and the activity, of nerve growth factor in the cerebrospinal fluid from the subject relative to the reference value representing a known health status indicates a diagnosis, or prognosis, or increased risk of the Alzheimer's disease in the subject.
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