Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
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United States of America Patent
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Issued Date -
Jun 9, 2005
app pub date -
Sep 29, 2004
filing date -
Nov 8, 1999
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Abandoned
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Abstract
A combination antibody therapy for treating B cell malignancies using an immunoregulatory antibody, especially an anti-B7, anti-CD23, or anti-CD40L antibody and a B cell depleting antibody, especially anti-CD19, anti-CD20, anti-CD22 or anti-CD37 antibody is provided. Preferably, the combination therapy will comprise anti-B7 and anti-CD20 antibody administration.
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