Treatment of restenosis
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United States of America Patent
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Issued Date -
Jun 2, 2005
app pub date -
Mar 10, 2004
filing date -
Mar 16, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
This invention relates to a method for inhibiting expression or activity of an adhesion molecule associated with an endothelial cell by contacting the adhesion molecule or endothelial cell with one or more isoflavone compounds or derivatives thereof. The invention also relates to a method of preventing or reducing the risk of restenosis after angioplasty, and to a method for the treatment or prophylaxis of atherosclerosis, coronary artery diseases, other cardiovascular diseases and inflammatory diseases mediated by adhesion molecules. The invention further relates to pharmaceutical compositions useful in these methods, and to methods for the manufacture of such medicaments.
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