Anti-angiogenesis methods
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Jun 2, 2005
app pub date -
Aug 30, 2004
filing date -
May 16, 2002
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
A method for inhibiting cell proliferation, cell migration, or tube formation induced by an angiogenic factor. The method includes administrating to a subject in need thereof an effective amount of a compound of the formula: 1 wherein A is H or 2 in which n is 0, 1, 2, or 3; each of Ar.sub.1, Ar.sub.2, and Ar.sub.3, independently, is phenyl, thienyl, furyl, pyrrolyl, pyridinyl, or pyrimidinyl; each of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6, independently, is R, nitro, halogen, C(O)OR, C(O)SR, C(O)NRR', (CH.sub.2).sub.mOR, (CH.sub.2).sub.mSR, (CH.sub.2).sub.mNRR', (CH.sub.2).sub.mCN, (CH.sub.2).sub.mC(O)OR, (CH.sub.2).sub.mCHO, (CH.sub.2).sub.mCH.dbd.NOR, or R.sub.1 and R.sub.2 together, R.sub.3 and R.sub.4 together, or R.sub.5 and R.sub.6 together are O(CH.sub.2).sub.mO, in which each of R and R', independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl; and m is 0, 1, 2, 3, 4, 5, or 6, and n is 0, 1, 2, or 3.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully