Fluorescent probes for ribosomes and method of use
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United States of America Patent
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Issued Date -
Jun 2, 2005
app pub date -
Sep 30, 2004
filing date -
Oct 3, 2003
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Abstract
Fluorescent probes that have binding affinity to ribosomes. The fluorescent probes are useful tools for identifying small molecules that bind to the 50S or 30S subunits of the bacterial and other ribosomes and serve as novel ribosome inhibitors. These probes are also useful for determining the interactions between a specific ligand and the ribosome.
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