Crystals and structures of protein kinase CHK2
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United States of America Patent
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Issued Date -
May 26, 2005
app pub date -
Jun 30, 2004
filing date -
Jul 1, 2003
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Abstract
The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of CHK2KD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of CHK2KD, CHK2KD crystals and compounds and compositions that affect CHK2 activity.
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