Crystals and structures of c-Abl tyrosine kinase domain

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United States of America Patent

APP PUB NO 20050107298A1
SERIAL NO

10851918

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of AblKD and variants and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator AblKD crystals and compounds and compositions that affect Abl activity.

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Patent Owner(s)

Patent OwnerAddress
SGX PHARMACEUTICALS INC10505 ROSELLE STREET SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arnold, William D San Diego, CA 38 1420
Buchanan, Sean Grant Encinitas, CA 13 30
Chie, Leon Barbara Chula Vista, CA 1 0
Louie, Gordon V San Diego, CA 5 3

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