Devices and methods for producing microarrays of biological samples

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United States of America Patent

APP PUB NO 20050106621A1
SERIAL NO

11022997

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Abstract

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The present invention is directed to systems and methods for producing microarrays of biological samples using an improved slide platform, vacuum manifold, and variable pin contact velocity. Slides onto which spotting pins produce the microarray of biological samples are secured on a flat slide platform using magnetic unit bars. The vacuum manifold effects optimal cleaning of the spotting pins by inducing increased air flow and turbulence. By reducing the velocity of the spotting pins before or after contact with the blot pad or the microarray slide, the morphology of biological samples deposited may be kept uniform. Similarly, low impact and separating velocities while acquiring biological materials prevent the pins from being overloaded with solution on the outside of the pin and causing sample wastage and non-uniform spotting.

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UNIVERSITY HEALTH NETWORK190 ELIZABETH STREET R FRASER ELLIOTT BUILDING - ROOM 1S-417 TORONTO M5G 2C4

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  • 2004 Application Filing Year
  • C12Q Class
  • 2673 Applications Filed
  • 714 Patents Issued To-Date
  • 26.72 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2004200520062007200820092010201120122013201420152016201720182019202020210255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
McNeil, James B Newmarket, CA 3 12
Winegarden, Neil A Burlington, CA 3 12

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  • 5 Citation Count
  • C12Q Class
  • 7.76 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges251664727137928341101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0102030405060708090100110120130140150160170180

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