Methods for the identification of inhibitors of biotin synthase expression or activity in plants

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United States of America Patent

APP PUB NO 20050101485A1
SERIAL NO

10702364

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Abstract

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The present inventors have discovered that Biotin synthase (BS) is essential for plant growth. Specifically, inhibition of BS gene expression in plant seedlings results in severe chlorosis and reduced growth. Thus, BS can be used as a target for the identification of herbicides. Accordingly, the present invention provides methods for the identification of compounds that inhibit BS expression or activity, and as such, the methods of the invention are useful for the identification of herbicides.

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Patent Owner(s)

Patent OwnerAddress
ICORIA INC108 ALEXANDER DRIVE POST OFFICE BOX 14528 PATENT & TRADEMARK DEPARTMENT RESEARCH TRIANGLE PARK NC 27709-4528

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ascenzi, Robert Cary, NC 43 44
Boyes, Douglas Chapel Hill, NC 29 222
Davis, Keith Durham, NC 67 876
Gorlach, Jorn Manchester, NJ 51 329
Hamilton, Carol Apex, NC 35 288
Hoffman, Neil Bethesda, MD 35 244
Woessner, Jeffrey Hillsborough, NC 25 192
Zayed, Adel Durham, NC 23 25

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