Characterization and isolation of subsets of human embryonic stem cells (HES) and cells associated or derived therefrom
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app pub date -
May 7, 2004
filing date -
Nov 9, 2001
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Abstract
A sub-population of HES cells is identified which is positive for specific HES markers. These cell types are identified by expression of particular GCTM-2 antigens. A method based on the identification of GCTM-2 can differentiate between substantially undifferentiated or differentiated cell populations. Spontaneous differentiation often occurs in HES cultures resulting in non-homogeneous cell cultures. The invention also provides further sub populations of cells within differentiated cultures of HES cells that are SCL or epithelial in nature.
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