Characterization and isolation of subsets of human embryonic stem cells (HES) and cells associated or derived therefrom

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United States of America Patent

SERIAL NO

10841907

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Abstract

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A sub-population of HES cells is identified which is positive for specific HES markers. These cell types are identified by expression of particular GCTM-2 antigens. A method based on the identification of GCTM-2 can differentiate between substantially undifferentiated or differentiated cell populations. Spontaneous differentiation often occurs in HES cultures resulting in non-homogeneous cell cultures. The invention also provides further sub populations of cells within differentiated cultures of HES cells that are SCL or epithelial in nature.

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Patent Owner(s)

Patent OwnerAddress
ES CELL INTERNATIONAL PTE LTDONE-NORTH 11 BIOPOLIS WAY HELIOS BLOCK #05-03/04-06 SINGAPORE 138667

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gion, Tomonobu Clayton, AU 1 15
Hawes, Susan Melanie Clayton, AU 1 15
Laslett, Andrew Clayton, AU 1 15
Pera, Martin Frederick Prahran, AU 18 330

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