3-Quinolin-2(1h)-ylideneindolin-2-one derivative
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United States of America Patent
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Issued Date -
Apr 28, 2005
app pub date -
Nov 24, 2003
filing date -
May 24, 2001
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Abandoned
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Abstract
There is provided medicaments, particularly a vascular endothelial growth factor (VEGF) inhibitor which is useful as a therapeutic drug for solid tumors, diabetic retinopathy and the like diseases in which angiogenesis is taking a role. That is, since a novel 3-quinolin-2(1H)-ylideneindolin--2-one derivative or a salt thereof has good VEGF inhibitory action, angiogenesis inhibitory action and anti-tumor action, it is useful as ideal VEGF inhibitor, angiogenesis inhibitor and anti-tumor agent.
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