Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium

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United States of America Patent

APP PUB NO 20050084928A1
SERIAL NO

10501777

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Abstract

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A glutamine-auxotrophic human cell transfected with an exogenous DNA sequence encoding a protein or an exogenous DNA sequence capable of altering the expression of an endogenous gene encoding a protein and an exogenous DNA sequence encoding a glutamine synthetase, wherein these exogenous DNA sequences are located on one or more than one DNA construct, said transfected cell capable of producing said protein and capable of growing in a glutamine-free medium.

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Patent Owner(s)

Patent OwnerAddress
LONZA BIOLOGICS PLC228-230 BATH ROAD SLOUGH BERKSHIRE SL1 4DX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Birch, John Robert Buckinghamshire, GB 2 115
Boraston, Robert Charles Buckinghamshire, GB 4 125
Shaw, Martyn Berkshire, GB 2 11

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