Spiro compounds and methods for the modulation of chemokine receptor activity
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United States of America Patent
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Issued Date -
Apr 7, 2005
app pub date -
Jul 19, 2004
filing date -
Jul 18, 2003
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Abstract
Novel compounds represented by formula I: 1 wherein Y, Z, X, W, R.sub.1, R.sub.2 and R.sub.3 are as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity and the treatment or prevention of diseases associated therewith.
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