Process for preparation of piperidin-2-ylacetic acid
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United States of America Patent
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Issued Date -
Apr 7, 2005
app pub date -
May 25, 2004
filing date -
Aug 21, 2001
priority date (Note) -
Abandoned
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Abstract
Piperidin-2-ylacetic acid (II) is efficiently and safely produced in industrial scale by treating piperidin-2-ylethanol (I) with 2,2,6,6-tetramethylpiperidin-1-oxyl, sodium hypochlorite and sodium chlorite in a two phase solvent comprising an organic solvent and water without using strongly toxic chromium trioxide.
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