Method of specifying snp
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United States of America Patent
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Issued Date -
Mar 31, 2005
app pub date -
Nov 18, 2004
filing date -
Jan 15, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention is intended to provide a technique relating to a method of specifying an SNP which comprises repeating presumption of an SNP serving as a marker and detailed typing of SNPs around the same, thus gradually narrowing down the focus to the base sequence domain in which the `target` SNP is likely contained and finally specifying the `target` SNP at a high efficiency. As FIG. 1 shows, the method of specifying an SNP comprises: (1) determining a drug to be developed which is the subject of the determination; (2) collecting samples to be analyzed; (3) determining a `scanning domain (base sequence domain)`; (4) determining `typing` SNPs; (5) SNP typing by the wet process and analyzing haplotypes based on the typing data; (6) presuming a `marker` SNP (determining the analytical data); and (7) specifying the `target` SNP (target SNP). A cycle consisting of the stage (1) to (7) is repeated as a treatment cycle.
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