Rapid disintegrating tablets (RDTs) for pharmaceutical use and method for preparing the same
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United States of America Patent
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Issued Date -
Mar 10, 2005
app pub date -
Sep 5, 2003
filing date -
Sep 5, 2003
priority date (Note) -
Abandoned
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Abstract
The present invention provides a fast-disintegrating tablet (RDT) and the method of preparing the RDT. The RDT contains a plurality of microcapsules which contains an active pharmaceutical ingredient surrounded by a polymeric matrix formed by a hydrogel. The microcapsules are separated from each other by a surfactant, particularly lecithin. The RDT is particularly suitable for use as a drug delivery system for antiacid or antiulcer drugs, such as famotidine. The RDT is further characterized by their its fast disintegration time of about 3 second to 3 minutes.
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