Bestrophin and bestrophin homologous proteins involved in the regulation of energy homeostasis
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United States of America Patent
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Issued Date -
Mar 3, 2005
app pub date -
Apr 8, 2004
filing date -
Oct 9, 2001
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Abstract
The present invention discloses Bestrophin homologous proteins regulating the energy homeostasis and the metabolism of triglycerides, and polynucleotides, which identify and encode the proteins disclosed in this invention. The invention also relates to the use of these sequences in the diagnosis, study, prevention, and treatment of diseases and disorders, for example, but not limited to, metabolic diseases such as obesity as well as related disorders such as eating disorder cachexia, diabetes mellitus, hypertension, coronary heart disease, hypercholesterolemia, osteoarthritis, gallstones, cancers of the reproductive organs, and sleep apnea.
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