Aminoalcohol derivatives and their use as beta 3 adrenergic agonists

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United States of America Patent

SERIAL NO

10746267

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Abstract

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A compound of the formula (I): 1 wherein X.sub.1 is bond or --OCH.sub.2--; X.sub.2 is --(CH.sub.2).sub.n--, in which n is 1, 2 or 3; X.sub.3 is bond, --O--, --S--, --OCH.sub.2--, or --NH--; R.sup.1 is phenyl or pyridyl each of which may have one or two substituent(s) selected from the group consisting of hydroxy, halogen, etc.; R.sup.2 is hydrogen, (lower)alkoxycarbonyl, etc.; R.sup.3 is hydroxy(lower)alkyl; halo(lower)alkyl, etc.; R.sup.4 is aryl or unsaturated heterocyclic group, each of which may have one or two substituent(s) selected from the group consisting of lower alkyl, hydroxy, carbamoyl, halogen, lower alkoxy, etc.; and a salt thereof which is useful as a medicament.

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Patent Owner(s)

Patent OwnerAddress
FUJISAWA PHARMACEUTICAL CO LTDOSAKA JAPAN OSAKA-SHI OSAKA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujii, Naoaki Osaka, JP 55 364
Ishikawa, Hirohumi Osaka, JP 2 20
Kato, Takeshi Hyogo, JP 272 4409
Kohno, Yutaka Osaka, JP 14 119
Sakurai, Minoru Osaka, JP 37 331
Takasugi, Hisashi Osaka, JP 144 1463
Taniguchi, Kiyoshi Hyogo, JP 42 324
Tomishima, Yasuyo Osaka, JP 14 65
Unami, Naoko Hyogo, JP 4 23
Washizuka, Kenichi Osaka, JP 13 45
Yamamoto, Nobuhiro Osaka, JP 67 176

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