Common ligand mimics: thiazolidinediones and rhodanines

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20040009526A1
SERIAL NO

10081989

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides common ligand mimics that act as common ligands for a receptor family. The present invention also provides bi-ligands containing these common ligand mimics. Bi-ligands of the invention provide enhanced affinity and/or selectivity of ligand binding to a receptor or receptor family through the synergistic action of the common ligand mimic and specificity ligand which compose the bi-ligand. The present invention also provides combinatorial libraries containing the common ligand mimics and bi-ligands of the invention. Further, the present invention provides methods for manufacturing the common ligand mimics and bi-ligands of the invention and methods for assaying the combinatorial libraries of the invention.

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Patent Owner(s)

  • TRIAD THERAPEUTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Edcon San Diego, US 18 228
Dong, Qing San Diego, US 131 1314
Fang, Yunfeng San Diego, US 20 126
Hansen, Mark San Diego, US 35 1125
Lang, Hengyuan San Diego, US 23 524
Pellecchia, Maurizio San Diego, US 50 191
Pierre, Fabrice La Jolla, US 42 576
Qin, Yong Poway, US 85 1289
Yu, Lin San Diego, US 87 856

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