Screening process for antibacterial agents
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United States of America Patent
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Issued Date -
Jan 27, 2005
app pub date -
Aug 17, 2004
filing date -
Nov 9, 1998
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method of preparing a phenotypically antibiotic-resistant subpopulation of stationary phase bacteria by treating stationary phase bacteria with high doses of antibacterial agents, the subpopulation thus identified, a process for identifying new antibacterial agents by testing against the antibiotic-resistant subpopulation, the compounds thus identified and their uses, particularly in treating bacterial infections involving dormant bacteria.
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