Label-free method for classification and characterization of cellular events
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United States of America Patent
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Issued Date -
Jan 20, 2005
app pub date -
Jul 14, 2003
filing date -
Jul 14, 2003
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Abstract
This invention incorporates the use of bioimpedance measurements of intact cells to classify and characterize any unique global cellular event such as signal transduction from ligand/receptor interactions, cytotoxicity, apoptosis, tumor cell progression, or stem cell differentiation. Specifically, we have demonstrated that this invention can classify signal transduction pathways from G-protein coupled, tyrosine kinase, and nuclear receptors.
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