TSG101 as inhibitor of HIV production
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United States of America Patent
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Issued Date -
Jan 13, 2005
app pub date -
Sep 18, 2003
filing date -
May 21, 2001
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Abandoned
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Abstract
The present invention provides methods for identifying peptides in a mammalian. Tsg101 protein that binds to the PTAPP motif or L domain of human immunodeficiency virus type I (HIV-1). Such peptides can be used to inhibit Tsg101-HIV Gag binding, and is therefore effective in reducing HIV particle production. The invention also provides the peptides identified by the method of the invention and to method of using such peptides for treating HIV infection.
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