Construction of Pasteurella haemolytica vaccines
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United States of America Patent
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app pub date -
Feb 4, 2004
filing date -
Dec 6, 1993
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Abstract
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect cattle.
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