Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine
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United States of America Patent
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Issued Date -
Jan 6, 2005
app pub date -
May 7, 2004
filing date -
May 7, 2003
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Abstract
The present invention describes derivatized polysaccharide-protein conjugates, a composition comprising one or more of such derivatized polysaccharide-protein conjugates and methods of immunizing human patients with the same. The derivatized polysaccharide-protein conjugates are purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W-135, and Y, derivatized chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains.
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