Biological markers for evaluating therapeutic treatment of inflammatory and autoimmune disorders
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United States of America Patent
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Issued Date -
Jan 6, 2005
app pub date -
May 12, 2004
filing date -
Sep 20, 2000
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Abandoned
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Abstract
Novel biological markers indicative of the action of an anti-inflammatory or immunosuppressive drug can be used to evaluate drug efficacy and compare local and systemic drug effects. They can also aid in comparison of different drugs, doses, and delivery routes. The biological markers include cell populations, cell surface antigen expression levels, and soluble factor concentrations. Measurement values of the novel biomarkers were shown to change significantly in allergic, atopic asthmatic, and healthy subjects after administration of prednisone.
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