Disease prevention by reactivation of the thymus
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Dec 23, 2004
app pub date -
Dec 30, 2003
filing date -
Apr 15, 1999
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The present disclosure provides methods for prevention and/or treatment of disease or illness in a patient by stimulating a patient's immune system through reactivation of the thymus. The patient's thymus is reactivated by interruption or ablation of sex steroid mediated signaling to the thymus, such as through the administration of LHRH agonists, LHRH antagonists, anti-LHRH receptor antibodies, anti-LHRH vaccines, anti-androgens, anti-estrogens, selective estrogen receptor modulators (SERMS), selective androgen receptor modulators (SARMS), aromatase inhibitors, or various combinations thereof. Non-limiting examples of illnesses or diseases that may be prevented or treated using the methods of the invention are those caused by viruses, bacteria, fungi, parasites, prions, cancers, allergens, asthma-inducing agents, or 'self' proteins and other antigens which cause autoimmune disease. In addition, optional gene therapy utilizing hematopoietic stem cells, lymphoid progenitor cells, and/or myeloid progenitor cells may be used in which the cells are administered to a patient in conjunction with treatment to reactivate the patient's thymus.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully