Novel neurotrophic factors
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United States of America Patent
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Issued Date -
Dec 23, 2004
app pub date -
Jul 23, 2004
filing date -
Jul 6, 2001
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Abstract
The present invention relates to novel biologically active, processed forms of the neuronal survival and growth factor protein denominated NSG3, in particular the pro-protein, the mature protein and core fragment of NSG3, as well as variants thereof. Also, the use of the novel polypeptides for treating or preventing a neurodegenerative disease, in particular an excitotoxic disease, a cancer, tissue injury, insufficient bone cartilage growth and maturation or a disease involving muscle in an animal is described.
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