Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby
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United States of America Patent
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Issued Date -
Dec 9, 2004
app pub date -
Jun 8, 2004
filing date -
Dec 28, 1999
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Abandoned
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Abstract
The invention relates to the field of biology. In particular, the invention relates to a method and system for designing optimized multi-epitope vaccines having selected combinations of spacer nucleic acid at the junctions of the multi-epitope constructs encoding a plurality of CTL and/or HTL eoutioe oeotudes so as to minimize the number of junciontal epitopes and provide vaccines with increased immunogenicity.
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