New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture

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United States of America Patent

APP PUB NO 20040242572A1
SERIAL NO

10647156

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Abstract

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The present invention relates to carboxamide compounds of general formula I 1 wherein the groups and residues A, B, W, X, Y, Z, R.sup.1, R.sup.2, R.sup.3 and k have the meanings given in claim 1. Moreover the invention relates to process for preparing the above mentioned carboxamides as well as pharmaceutical compositions containing at least one carboxamide according to the invention. In view of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.

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Patent Owner(s)

Patent OwnerAddress
BOEHRINGER INGELHEIM INTERNATIONAL GMBHBINGER STRASSE 173 INGELHEIM AM RHEIN 55216

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arndt, Kirsten Biberach, DE 51 665
Lehmann-Lintz, Thorsten Ochsenhausen, DE 48 698
Lenter, Martin Ulm, DE 20 350
Lotz, Ralf RH Schemmerhofen, DE 15 711
Lustenberger, Philipp Warthausen, DE 86 861
Mueller, Stephan George Warthausen, DE 2 27
Rudolf, Klaus Warthausen, DE 136 1766
Stenkamp, Dirk Biberach, DE 88 1141
Wieland, Heike-Andrea Bad Soden, DE 6 63

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