Method of selecting non-pathogenic gram-positive lactic acid bacteria strains
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United States of America Patent
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Jul 13, 2004
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Jun 14, 2001
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Abstract
The invention relates to a method of selecting non-pathogenic Gram-positive lactic acid bacteria strains that can combat infections by pathogenic bacteria for which the pathogenicity is the result of a tissue adhesion. The inventive method consists in choosing a strain presenting all of the following properties: a) the ability to adhere to tissues of an organ that is likely to be infected; b) the ability of the bacteria of said strain to fix to one another via mutual adhesion sites; and c) the ability to fix to the attachment determinants of the pathogenic bacterial strain responsible for the infection. The bacterial strains thus selected can be used in the production of therapeutic compositions that are intended to prevent or treat pathological conditions associated with the infection of the host's organ by pathogenic bacterial strains.
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